A randomized cross-over study on the inhibitory effect of rice peptide on plaque formation

A randomized cross-over study on the inhibitory effect of rice peptide on plaque formation - The effect of rice peptide on plaque formation

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000011982

Enrollment

Registered

2013-11-01

Start date

2013-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontal disease

Interventions

Subjects are instructed to use 20 ml rice peptide mouth rinse (0.4%) twice a day (in the morning and evening) and stop tooth brushing during 3 days period. Control (placebo mouth rinse group)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Those with good general health. 2. Periodontally healthy individuals 3. Those who agreed to participate in the study with written informed consent.

Exclusion criteria

Exclusion criteria: 1. Those with uncontrolled systemic disease 2. Those who received antimicrobial or steroid treatment during the study. 3. Those with untreated dental disease 4. Those with severe malocclusion 5. History of allergic reaction against rice or medication 6. Those who used other oral care material during the study. 7. Those who are judged to be inappropriate to be included in the study by principal investigator or dentist

Design outcomes

Primary

Measure	Time frame
To compare the level of plaque formation between the experimental group with rice peptide rince and the control group	—

Secondary

Measure	Time frame
Questionnaire survey about rice peptide mouth rinse	—

Countries

Japan

Contacts

Public ContactSaori Takayama

Tokyo Dental College Department of Periodontology

saoritakayama@tdc.ac.jp043-270-3954

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026