The significance of the state of muscularis mucosae (MM grade) as a new risk factor for nodal metastasis in considering the indication for additional surgical colectomy with lymph node dissection among submucosal-invasive (T1) colorectal carcinomas after endoscopic treatment

The significance of the state of muscularis mucosae (MM grade) as a new risk factor for nodal metastasis in considering the indication for additional surgical colectomy with lymph node dissection among submucosal-invasive (T1) colorectal carcinomas after endoscopic treatment - The significance of the state of muscularis mucosae (MM grade) as a risk factor for nodal metastasis in considering the indication for additional surgical colectomy among T1 colorectal carcinomas after endoscopic treatment

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000011974

Enrollment

800

Registered

2013-10-07

Start date

2013-10-07

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal carcinomas

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: A total of more than 20000 colorectal neoplasms excluding advanced cancers have been resected endoscopically or surgically at Showa University Northern Yokohama Hospital from 2001 to 2013. Of these, approximately 800 T1 colorectal cancers were included.

Exclusion criteria

Exclusion criteria: People not grown up

Design outcomes

Primary

Measure	Time frame
To clarify pathological risk factors for lymph node metastasis of T1 colorectal cancers, confirming the significance of the state of muscularis mucosae (MM grade).	—

Secondary

Measure	Time frame
To establish the indication for additional surgical colectomy with lymph node dissection, based on the pathological risk factors of the excised specimen after endoscopic treatment.	—

Countries

Japan

Contacts

Public ContactHideyuki Miyachi

Showa University Northern Yokohama Hospital Digestive Disease Center

miyachi@med.showa-u.ac.jp045-949-7265

Outcome results