Esophagealcancer
Conditions
Interventions
Elental (1 pack per day) during radiation or chmeradiation
No administration of Elental
Sponsors
Department of Gastroenterology, Toranomon Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Histologically confirmed esophageal cancer 2.lesions located in the thoracic esophagus 3. M3 or deeper 4. No prior chemo(-radio)therapy 5. over 20 and under 80 years of age 6. PS 0-2 7. Adequate oragn functions 8. Written informed consent
Exclusion criteria
Exclusion criteria: 1. patients withe the past history of allergy to iodine 2. patients without cessation of anticoagulant therapy 3. Presence of other cancer 4. Pregnant or nursing women and those with the possibility of pregnancy 5. Mental or neurologic disease that might affect participation 6. Receiving steroid therapy 7. Positive HBs Antigen 8. Active infection 9. Presence of recent MI or history of unstable AP 10. Presence of uncorolled diabetes 11. Presence of uncontrolled hypertention 12. Presence of IP, pulmonary fibrosis, or severe CPE 13. patients with the past history of hypersensitivity to Elental 14. Abnormality in amino acid metabolism 15. patients considered inadequate for inclusion in this trial by the physician
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Frequency or severity of oral erosion | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Frequency of diarrhea, nausea or vomitting 2.Frequency of comlpetion of chemoradiotherapy of chemotherapy 3.decrease of Nutrition marker 4.loss of body weight 5.intake of Elental | — |
Countries
Japan
Contacts
Public ContactToshiro Iizuka
Toranomon Hospital Department of Gastroenterology
Outcome results
None listed