Effect of epigallocatechin supplementation on the immune response to influenza vaccination

Effect of epigallocatechin supplementation on the immune response to influenza vaccination - Epigallocatechin and immune response to influenza vaccination

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000011951

Enrollment

180

Registered

2013-10-08

Start date

2013-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Influenza infection

Interventions

Supplementation of EGC (3.0 mg/dL) for 4 months in subjects &lt

65 years. Supplementation of EGC (1.5 mg/dL) for 4 months in subjects &lt

65 years. Supplementation of placebo tea for 4 months in subjects &lt

65 years. Supplementation of EGC (3.0 mg/dL) for 4 months in subjects &amp

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70 years. Supplementation of EGC (1.5 mg/dL) for 4 months in subjects &amp

70 years. Supplementation of placebo tea for 4 months in subjects &amp

70 years.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Subjects who are recruited in the Osaka Medical College (n=90) and subjects in the Aiwa geriatric health services facilities (n=90).

Exclusion criteria

Exclusion criteria: Subjects who are in the bad health condition, those who cannot safely ingest EGC-containing Tea, and those who are taking corticosteroid or other immuno-suppressive agents will be excluded from the study.

Design outcomes

Primary

Measure	Time frame
Rate of influenza-infection symptoms and antibody titer to influenza after the influenza vaccination	—

Secondary

Measure	Time frame
The extent of cytokine production by lymphocyte fraction after antigen stimulation by ELISPOT method	—

Countries

Japan

Contacts

Public ContactKoichi Sohmiya

Osaka Medical College Internal Medicine3

omc3nai-group@umin.ac.jp072-683-1221

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026