Feasibility study of UFT/LV as adjuvant chemotherapy for stage III colorectal cancer in elderly patients (over 80 years old)

Feasibility study of UFT/LV as adjuvant chemotherapy for stage III colorectal cancer in elderly patients (over 80 years old) - Feasibility study of adjuvant chemotherapy for colorectal cancer in elder patients

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000011899

Enrollment

Registered

2013-11-01

Start date

2013-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer

Interventions

UFT+UZEL

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Clorectal cancer patients (Histologically confirmed) 2.Stage III colorectal cancer patients 3.patients who underwent R0 resection 4.ECOG Performance status: 0-2 5.80 years old or more 6.No previous history of chemotherapy or radiotherapy for colorectal cancer 7. Within 8 weeks after operation 8.Adequate organ functions 9.Oral food intake possible 10.Written informed consent

Exclusion criteria

Exclusion criteria: 1.History of serious drug hypersensitivity 2.Wattery diarrhea 3.Cases with severe postoperative complication 4.Males with female partners who are planning to pregnancy 5.Severe comorbidity 6.Synchronous or metachronous multiple malignancy within the last 5 year disease free interval 7.Any other serious or uncontrolled condition which, in the opinion of the investigator, makes it undesirable for the patient to enter the trial

Design outcomes

Primary

Measure	Time frame
Feasibility	—

Secondary

Measure	Time frame
Safety, Overall survival, Disease free survival, Relative Dose Intensity	—

Countries

Japan

Contacts

Public ContactHinoi Takao

Hiroshima University Hospital Dept, of Gastroenterological and transplant surgery

thinoi@hiroshima-u.ac.jp082-257-5222

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026