resectable or borderline resectable pancreatic cancer undergoing neo-adjuvant chemotherapy
Conditions
Interventions
None listed
Sponsors
The University of Tokyo
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Biliary drainage using a paritially-covered SEMS 2) Scheduled for neoadjuvant chemotherapy or chemoradiotherapy 3) Distal malignant biliary obstruction due to pancreatic cancer 4) Age 20 or older 5) Willing and able to comply with the study procedures and provide written informed consent to participate in the study
Exclusion criteria
Exclusion criteria: 1) Location of distal biliary obstruction such that it would not allow the proximal end of a stent to be positioned at least 2 cm from the hilum 2) Patients with duodenal obstruction anal to the ampulla 3) Tumor involvement to the orifice of cystic duct 4) Previous biliary drainage by ENBD or EBD more than 2 weeks 5) Patients with severely impaired organ function 6) Patients for whom endoscopic biliary drainage is difficult 7) Patients with distant metastasis 8) Hilar biliary obstruction 9) Without pathological diagnosis 10) Patients considered ineligible for this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of recurrent biliary obstruction prior to surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to recurrent biliary obstruction (TRBO), adverse events, overall survival, stent removal at the time of surgery. | — |
Countries
Japan
Contacts
Public ContactKei Saito
The University of Tokyo Gastroenterology
Outcome results
None listed