chronic heart failure
Conditions
Interventions
Adaptive servo-ventilation
without adaptive servo-ventilation
Sponsors
Department of Cardiovascular and Medicine, Akita University Graduate School of Medicine,
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with chronic heart failure 1) NYHA II or III 2) LVEF<45% 3) stable HF patients whose prescriptions are not changed more than 1 month 4) conventional medical therapy is performed
Exclusion criteria
Exclusion criteria: 1) patients undergoing positive airway pressure 2) patients undergoing hemodialysis 3) chronic and acute inflammation disease or malignant disease 4) phyaryngial disease 5) patients who could not have conventional medical therapy 6) uncontrolled diabetes and hypertension 7) hepatitis, liver cirrhosis, liver cancer, joundice 8) acute coronary syndrome 9) patients who will have heart surgery 10) pregnant 11) patients who will have pacing therapy 12) patients who have serious cerebrovascular disease 13) patients who have intravenous administration for heart failure 14) chronic renal failure (Cre>=3.0) 15) serious respiratory disease 16) subjects whose doctor in charge do not agree to join the trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cardiovascular events | — |
Secondary
| Measure | Time frame |
|---|---|
| Plasma norepinephrine, serum creatinine, microalbuminurea, eGFR, hs-CRP, Hb, BGA, LVEF, Dd, Ds, LVEDV, LVESV, E/A, E/e', LA volume, BNP, administration changes due to HF worsening, polysomnography, respiratory function data | — |
Countries
Japan
Contacts
Public ContactTakashi Koyama
Akita University Graduate School of Medicine Department of Cardiovascular Medicine
Outcome results
None listed