Study of the clinical effects by the central supply method of the acetic acid-free dialytic fluid

Study of the clinical effects by the central supply method of the acetic acid-free dialytic fluid - clinical effects of the acetic acid-free dialytic fluid

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000011765

Enrollment

Registered

2013-09-17

Start date

2010-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

end-stage renal failure

Interventions

six months of Acetic acid component dialytic fluid use, and then 12 months of acetic acid-free dialytic fluid use

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: end-stage renal failure patients with stable outpatient maintenance hemodialysis 20 years or older

Exclusion criteria

Exclusion criteria: hemodialysis patients without any cancer or acute Inflammation

Design outcomes

Primary

Measure	Time frame
For a hemodialysis patient, we examine a 12-month clinical response of acetic acid-free dialytic fluid after use in acetic acid dialytic fluid for six months. Examination item are dialysis efficiency (Kt/V), a circulation change (mean blood pressure and the pulse), nourishment dialyzing are in a state (serum protein and albumin, nPCR), acidotic improvement effect (pH, HCO3-, BE).	—

Secondary

Measure	Time frame
For a hemodialysis patient, we measure a 12-month oxidation stress marker of acetic acid-free dialytic fluid after use in acetic acid dialytic fluid for six months. Examination item are blood reduced glutathione/oxidized glutathione ratio and serum MDA-LDL.	—

Countries

Japan

Contacts

Public ContactKaori Ishizeki

National Defense Medical College Hospital Department of Blood Purification

halfmoon@ndmc.ac.jp04-2995-1511

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026