prediabetes
Conditions
Interventions
12 weeks, 4 tablets / day Placebo group
12 weeks, 4 tablets / day AP600mg group
12 weeks, 4 tablets / day AP900mg group
Sponsors
National Institute of Fruit Tree Science, National Agriculture & Food Research
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: fasting blood glucose 100<=130>=
Exclusion criteria
Exclusion criteria: A person who has regular supplements such as grape seed and tea polyphenols. A person who has participated in other clinical trials in this study at the start. So far, by ingestion of polyphenol and Apple, who has ever complained of a disorder of the body. 1. A person with a history heart failure, myocardial infarction. 2. Treatment of atrial fibrillation, hypertension, arrhythmia, liver failure, renal failure, cerebrovascular disease, arthritis, diabetes, hyperlipidemia, such as anemia. 3. A person have (food, medicine) and allergy history. 4. Pregnant women, nursing mothers 5. Others, who the investigator has determined to be inappropriate as a target for this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glucose, insuline | — |
Secondary
| Measure | Time frame |
|---|---|
| C-peptide, TNF-a, IL-6, IL-1b, leptin, adiponectin, PAI-1, MCP-1, GLP-1 | — |
Countries
Japan
Contacts
Public ContactMitsuhiro Yamada
Kakegawa city Health and Prevention Division
Outcome results
None listed