hepatic carcinoma
Conditions
Interventions
Patients who suspected HCC are prospectively enrolled, and these patients will undergo contrast enhanced CT and EOB enhanced MRI (T1WI, T2WI, DWI, and enhanced T1WI).
Sponsors
Department of Radiology doctors' office, University of Yamanashi hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Step 1: Patients with final pathological diagnosis of liver tumors (including those other than HCC) for which EOB-enhanced MRI was performed before pathological diagnosis Inclusion criteria: Patients who meet all of the following criteria are included. 1.Patients who have chronic hepatic disease 2.Patients who underwent EOB-enhanced MRI 3. Patients with final pathological diagnosis of liver tumors (including those other than HCC) 4. Patients who are 20 years or older Step 2: Patients with suspected HCC who are expected to undergo EOB-enhanced MRI Inclusion criteria: Patients who meet all of the following criteria are included. 1. Patients who have chronic hepatic disease 2.Patients who are expected to undergo EOB-enhanced MRI and dynamic CT scan 3. Both inpatients and outpatients 4. Patients who are 20 years or older 5. Patients with clear consciousness
Exclusion criteria
Exclusion criteria: Step 1: Patients who meet any of the followingcriteria are not included in this study. 1. Patients who are judged to be inappropriate by the physician in charge Step 2: Patients who meet any of the following criteria are not included in this study. 1. Patients who are contraindicated or relatively contraindicated for iodine contrast agents and gadolinium contrast agents 2. Child-Pugh C 3. Patients with diffuse liver tumors 4. Patients who are judged to be inappropriate by the physician in charge (patients in terminal care, etc.)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnosability (sensitivity, specificity, PPV, NPV, and positive/negative likelihood ratio) using typical findings of HCC by EOB-enhanced MRI (low signal intensity in the hepatocyte phase plus other findings) is compared to that of dynamic CT | — |
Countries
Japan
Contacts
Public ContactTomoaki Ichikawa
University of Yamanashi hospital Department of Radiology
Outcome results
None listed