Effects of collagen membrane for combination therapies with regenerative materials of enamel matrix derivative and xenogeneic bone graft for periodontal surgery.

Effects of collagen membrane for combination therapies with regenerative materials of enamel matrix derivative and xenogeneic bone graft for periodontal surgery. - Combination therapies with EMD, xenogeneic bone and collagen membrane.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000011709

Enrollment

Registered

2013-09-11

Start date

2013-09-12

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontitis

Interventions

In periodontal tissue regeneration procedure, after the root surface debridement, Enamel Matrix Derivative is applied on the root surface and deproteinized bovine bone matrix is filled in bone defect.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with periodontitis accompanied with proving pocket depth more than 6mm deep and vertical infra bony defect after initial periodontal therapy, are selected.

Exclusion criteria

Exclusion criteria: Patients with following conditions are excluded from subjects: patients with pre-existing severe diseases such as diabetes mellitus, cardiovascular disease and autoimmune disease etc.

Design outcomes

Primary

Measure	Time frame
1) bone level 2) clinical attachment level	—

Countries

Japan

Contacts

Public ContactYasuko Nemoto

Niigata University Division of Periodontology

yasuko@kyi.biglobe.ne.jp+8125227871

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026