food allergy
Conditions
Interventions
s milk, and 100g of Japanese Udon noodles. The subjects are asked to take a small amount of their causative food at home, and it is built up to target amount gradually depending on their symptoms.
with antihistamine group"
which use it during the build up phase. The other group is "
without antihistamine group"
which do not use It.
Sponsors
National Hospital Organization Sagamihara National Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Subjects are confirmed mild or moderate positive objective symptoms caused by hen's egg, cow's milk, or wheat ingestion challenge just before this trial.
Exclusion criteria
Exclusion criteria: The threshold for eliciting positive symptoms is less than one fourth hen's egg, 12ml of cow's milk, or 7g of Udon noodles by oral food challenge test. The subject who is treated by adrenaline injection at oral food challenge test just before this study. The subject who has not-well treated atopic dermatitis, bronchial asthma, or any underlying disease. The subject who is not appropriate for oral immunotherapy, judged by medical doctor.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The purpose of this study is to clarify outcome, regarding tolerance acquisition and incidence rate of symptoms by outpatient slow oral immunotherapy. | — |
Secondary
| Measure | Time frame |
|---|---|
| To investigate the efficacy of oral immunotherapy, compared to natural course without this therapy. To confirm the safety of outpatient oral immunotherapy for mild and moderate food allergic children. To analyze the incidence rate of symptoms with or without using antihistamine drug during build-up phase. | — |
Countries
Japan
Contacts
Public ContactImai Takanori
National Hospital Organization Department of Allergy, Clinical Research Center for Allergy and Rheumatology
Outcome results
None listed