constipation
Conditions
Interventions
Intake 2 g of Okara powder contained Bacillus coagulans lilac-01 dairy for two weeks.
Intake 2 g of Okara powder (placebo food) dairy for two weeks.
Sponsors
Hokkaido Information University
Aterio bio Co., Inc.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Subjects suffered from constipation Subjects we obtained written informed consent for participation in the study.
Exclusion criteria
Exclusion criteria: (1) Subjects with a history of gastrointestinal cancer (2) Subjects with serious disease and infection (3) Subjects with previous gastrointestinal surgery (4) Subjects with IBS (5) Subjects with a history of allergy to medicine and food, especially soy bean. (6) heavy smokers and alcohol addict and subjects that spend irregular lifestyle. (7) Subjects who donate 200ml or more of blood within 4 wks, or who donate 400ml or more of blood within 12 wks before screening or subjects who donate plasma or platelet within 4 wks before supplementation started. (8) There is possibility of the inside of the present pregnancy or pregnancy, or it is under breast-feeding. (9) Subjects who participated in other clinical trials within the past one months before the start of this clinical trial. (10) Subjects whom the attending physician judges to be an inappropriate subject.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| questionnaire for defecatory conditions | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS, fecal microbiota, fecal water content, fecal pH, fecal oeganic acid content, fecal ammonium, fecal substrate decomposition, fecal bile acid | — |
Countries
Japan
Contacts
Public ContactDirector of center. Nishihira, Jun
Hokkaido Information University Health Information Science Center
Outcome results
None listed