Gastric and colon cancer
Conditions
Interventions
Administration of Enoxaparin(2000IU twice a day, POD1-7) and mechanical thromboprophylaxis(POD1)
mechanical thromboprophylaxis(POD1)
Sponsors
Gastroenterological Surgery 1 Hokkaido Univ. Graduated School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Postoperative function of the major organs(bone marrow, liver, kidneys, etc.) are held sufficiently; patients that meet the following criteria (hemoglobin : 9.5g/dl or more, ALT and AST: 2.5 times less than the normal value of the facility, total bilirubin: 3.0mg/dl or less, SpO2: 90% or more).
Exclusion criteria
Exclusion criteria: 1)Patients with heparin-induced thrombocytopenia or patients with a history of hypersensitivity of to heparin or related substances(HIT). 2)Patients with acute bacterial endocarditis 3)Patients with severe to moderate renal dysfunction(creatinine clearance below 50mL/min). 4)Patients with severe liver failure. 5)Low-weight patients (weight less than 40kg) 6)Women who may possibly be pregnant or are pregnant. 7)Patients receiving antiplatelet drugs (such as clopidogrel or aspirin) or anticoagulant drugs (warfarin etc.) affecting hemostasis preoperatively. 8)Patients with venous thromboembolic disease was observed within one year prior to surgery of this study or the patient with clinical signs or merger of deep vein thrombosis. 9)Ppatients with contraindications of iodinated contrast agent. 10)Patients who have indwelling central venous catheter. 11)Patients treated with progesterone and estrogen formulation within 4 weeks before administration. 12)Patients receiving radiation therapy or systemic cancer chemotherapy within two weeks before the administration. 13)Patients is determined inappropriate as a test target by principal investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of VTE. | — |
Countries
Japan
Contacts
Public ContactHirofumi Kamachi
Hokkaido Univ. Graduated School of Medicine Gastroenterological Surgery 1
Outcome results
None listed