The impact of continuous positive airway pressure (CPAP) on aortic aneurysms in patients with obstructive sleep apnea

The impact of continuous positive airway pressure (CPAP) on aortic aneurysms in patients with obstructive sleep apnea - The impact of CPAP on aortic aneurysms in patients with OSA

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000011592

Enrollment

Registered

2014-01-01

Start date

2014-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

obstructive sleep apnea aortic aneurysm

Interventions

Patients with apnea-hypopnea index (AHI)&gt

20 CPAP treatment (during sleep, everyday) Patients with apnea-hypopnea index (AHI)&lt

20 No treatment

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with thoracic aortic aneurysm (TAA) or abdominal aortic aneurysm (AAA) 2. Diameter of aortic aneurysm has been measured by CT for at least one year 3. Receiving appropriate treatments for hypertension, dyslipidemia, and/or diabetes

Exclusion criteria

Exclusion criteria: 1. Previous or current treatments for sleep apnea. 2. Previous treatment for aortic aneurysm 3. Planned intervention for aortic aneurysm 4. Central sleep apnea syndrome 5. Long-term oxygen therapy 6. Aortic aneurysm associated with hereditary diseases (e.g. Marfan syndrome) 7. Unable to use CPAP 8. Hope for treatments other than CPAP for OSA 9. Surgery of upper airway within 90 days

Design outcomes

Primary

Measure	Time frame
The changes in the expansion rate of aortic aneurysms (mm/year) before and after the CPAP treatment	—

Secondary

Measure	Time frame
1. Expansion rate (mm/year) of aortic aneurysms in patients without CPAP treatment 2. Prevalence of OSA in patients with aortic aneurysm 3. Events associated with aortic aneurysm 4. Cardiovascular events 5. Changes in biomarkers of aortic aneurysm 6. Changes in blood pressure and endothelial function 7. Changes in epicardial fat and visceral fat volume 8. Changes in sleep duration	—

Countries

Japan

Contacts

Public ContactKazuo Chin

Graduate School of Medicine, Kyoto University Respiratory Care and Sleep Control Medicine

ryotkw@gmail.com81-(0)75-751-3852

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026