Opioid Tolerance: Can it be quantitatively assessed?

Opioid Tolerance: Can it be quantitatively assessed? - Assessment of Opioid Tolerance

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000011580

Enrollment

Registered

2013-08-27

Start date

2013-08-27

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Elective surgery patients

Interventions

No treatment control Opioid consuming patient for cancer or chronic pain

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Elective surgery patient American Society of Anesthesiologist PS 1-2 Capable communication in Japanese Willing to attend

Exclusion criteria

Exclusion criteria: Skin erosion or hypoesthesia in the area of pain pressure measurement Patient started on opioid analgesic within 1 week of the surgery

Design outcomes

Primary

Measure	Time frame
Comparison of pain sensation pressure and non-respiratory sensation period after bolus administration of fentanyl amongst opioid naive and tolerant patients.	—

Secondary

Measure	Time frame
Comparison of the changes in pain sensation pressure and non-respiratory sensation period after bolus administration of fentanyl amongst opioid naive and tolerant patients.	—

Countries

Japan

Contacts

Public ContactNatsuko Nozaki-Taguchi

Chiba University Hospital Anesthesiology and Palliative Medicine

nnoztag@faculty.chiba-u.jp043-226-2303

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026