Evaluation of thermosensitive atelocollagen punctal plug (Keeptear) treatment

Evaluation of thermosensitive atelocollagen punctal plug (Keeptear) treatment - Evaluation of Keeptear punctal plug treatment

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000011574

Enrollment

Registered

2013-09-01

Start date

2009-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry eye disease

Interventions

Keeptear punctal plug treatment Standard punctal plug treatment

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Dry eye disease (2006 Japanese dry eye criteria)

Exclusion criteria

Exclusion criteria: Any history with punctal plug insertion or surgical occlusion of punctum

Design outcomes

Primary

Measure	Time frame
Vital staining score Tear volume measurement Tear clearance test	—

Secondary

Measure	Time frame
Visual analog score (VAS)	—

Countries

Japan

Contacts

Public ContactTakashi Kojima

Keio University School of Medicine Department of Ophthalmology

tkojkoj@mac.com03-5363-2012

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026