Research of early diagnosis and treatment with the examination of High Resolution Anoscopy (HRA) of anal canal squamous cell carcinoma caused by human papilloma virus (HPV)

Research of early diagnosis and treatment with the examination of High Resolution Anoscopy (HRA) of anal canal squamous cell carcinoma caused by human papilloma virus (HPV) - Early diagnosis and treatment of HPV-related anal canal SCC with HRA

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000011546

Enrollment

Registered

2013-10-01

Start date

2014-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Human Papilloma Virus(HPV)-related anal canal squamous cell carcinoma

Interventions

High Resolution Anoscopy (HRA) examination

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: HIV-seropositive patients (not onset of AIDS) revealed to be detected dysplasia by APS

Exclusion criteria

Exclusion criteria: Cases of advanced cancer at the time of initial examination and/or cases which cannot be inspected because of significant psychiatric and neurological disorders

Design outcomes

Primary

Measure	Time frame
Incidence of dysplasia, carcinoma in situ of patients with APS-positiveness (Anal Intraepithelial Neoplasia [AIN] 1-3)	—

Secondary

Measure	Time frame
1. The sensitivity and specificity of APS about AIN grade using HRA 2. Identification of high-risk HPV genotype in Japan 3. Relevance between the incidence of dysplasia and CD4+ count, HIV-viral load using biopsy specimens harvested by HRA	—

Countries

Japan

Contacts

Public ContactHiroshi Kitamura

Kyorin University Faculty of Medicine Department of Medical Oncology

hkitamura3539@ks.kyorin-u.ac.jp0422-47-5511

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026