A Study on the Effects of Cetylpyridinium Chloride Oral Ointment Containing Phosphorylated Pullulan on Oral Microflora and Oral Mucosa

A Study on the Effects of Cetylpyridinium Chloride Oral Ointment Containing Phosphorylated Pullulan on Oral Microflora and Oral Mucosa - A Study on the Effects of CPC Oral Ointment Containing Phosphorylated Pullulan

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000011530

Enrollment

Registered

2013-08-20

Start date

2013-08-21

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stomatitis and Xerostomia

Interventions

cetylpyridinium chloride oral ointment containing phosphorylated pullulan and ointment base cetylpyridinium chloride oral ointment containing phosphorylated pullulan and cetylpyridinium chloride o

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: dentists with oral and systemic health

Exclusion criteria

Exclusion criteria: inflammation in oral cavity pre-existing diseases any medication

Design outcomes

Primary

Measure	Time frame
1) reduction of oral bacterial DNA amount by quantitative analysis using polymerase chain reaction method 2) preserved pattern of oral bacterial DNA by evaluation using terminal restriction fragment length polymorphism method 3) preserved moisture on oral mucosa by measurement using oral mucosa moisture checker 4) no inflammation on oral mucosa by clinical observation	—

Secondary

Measure	Time frame
Questionnaire 1) acceptable sensation on oral mucosa 2) no irritative sensation on oral mucosa	—

Countries

Japan

Contacts

Public ContactShogo Takashiba

Okayama University Department of Pathophysiology - Periodontal Science, Graduate School of Medicine, Dentistry and Pha

stakashi@cc.okayama-u.ac.jp086-235-6675

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026