post-ERCP pancreatitis
Conditions
Interventions
mixed amino acid medication
regular diet
Sponsors
Yokohama City University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: "Patient-related risk factors" 1) age younger than 60 years old, 2) female sex, 3) suspected bilialy sphincter of Oddi dysfunction (SOD), 4) history of recurrent pancreatitis, and 5) history of PEP. "Procedure-related risk factors"1) pancreatography, 2) endoscopic pancreatic sphincterotomy (EST), 3) pre-cut sphincteroromy, 4) difficulty of procerure (> 30 min), 5) dificulty of cannulation (> 6 times or > 15 min), 6) pancreatic tissue sampling, 7) biliary biopsy or brushing cytology, 8) intraductal ultrasonography (IDUS), 9) endoscopic balloon dilatation (EPBD), 10) endoscopic papillectomy (EP), 11) Self-expandable metallic stent (SEMS) placement and 12) trainee involvement in the ERCP.
Exclusion criteria
Exclusion criteria: 1) who we could not achieve informed concent, 2) who we evaluated inappropriate for thos trial, 3) who had poor performance status, 4) were under 20 years old, 5) to who ERCP was not completed, 6) who had acute or active pancreatitis, and 7) who had low risk factors of PEP: a) choronic pancreatitis, b) periodical stent exchange, c) ERC to pancreas divisum, and d) the past history of papilla disposal (ex. EST, EPBD and EP).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1) new abdominal pain. 2) eleuation in pancreatic enzymes to at least three times the upper limit of the normal range 24 hours after ERCP. 3) extension of hospitalization or medical treatment at least two days. | — |
Secondary
| Measure | Time frame |
|---|---|
| adverse event | — |
Countries
Japan
Contacts
Public ContactTakamitsu Sato
Yokohama City University Hospital Gastroenterology Division
Outcome results
None listed