Effects of herbal medicine Daikenchuto on the patients of refractory lower urinary tract symptoms or overactive bladder with constipation or hypersensitivity to cold

Effects of herbal medicine Daikenchuto on the patients of refractory lower urinary tract symptoms or overactive bladder with constipation or hypersensitivity to cold - Effects of Daikenchuto on the patients of lower urinary tract symptoms with constipation or hypersensitivity to cold

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000011513

Enrollment

Registered

2013-08-20

Start date

2012-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

overactive bladder / lower urinary tract symptoms

Interventions

Administration of Daikenchuto (15.0g/day, p.o.) for 1 month

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Refractory LUTS/OAB patients were defined as LUTS/OAB patients who had not been controlled well under conventional drugs including alpha-blocker, anticholinergic drug, and 5-alpha-reductase inhibitor.

Exclusion criteria

Exclusion criteria: Patients were excluded if they had confirmed prostate cancer, acute or chronic prostatitis within the previous 3 months, serum prostate-specific antigen levels over 4 ng/mL, a history of recurrent urinary tract infection or bladder stones, and previous transurethral resection of prostate or other surgical intervention related to bladder or prostate cancer.

Design outcomes

Primary

Measure	Time frame
international prostate symptom score (IPSS), quality of life (QOL) score, and overactive bladder symptom score (OABSS)	—

Secondary

Measure	Time frame
voided volume, Qmax, Qave, and residual urine volume	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026