sepsis
Conditions
Interventions
the group (TPTD group) which performed fluid management by the transpulmonary thermodilution method
the group (CVP group) which performed fluid management by using central venous pressure
Sponsors
St. Marianna University School of Medicine Department of Emergency and Critical Care Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: A. Sepsis: infection focus and two items or more of following SIRS items corresponds. a. Temperature >38C or <36C b. Heart rate > 90/min c. Number of breathing >20/min or PaCO2<32 mmHg d. Leukocyte >12000/mu l or <4000/micro l B. expected to require mechanical ventilatory support in ICU for at least 48 hours
Exclusion criteria
Exclusion criteria: Below 18 years of age,Pregnant women,Burns,Drug intoxication,Severe acute pancreatitis,Intracranial vascular lesions,Coronary artery disease,24 hours or more have passed after meeting a selection criteria,TPTD measurement is difficult,under percutaneous-cardiopulmonary-support equipment (PCPS),Present of DNAR,Occurrence of arrhythmia,Physician's discretion
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ventilator-free days at 28 days | — |
Secondary
| Measure | Time frame |
|---|---|
| Probability of survival during 28 days, length of ICU stay, water balance for three days | — |
Countries
Japan
Contacts
Public ContactKenichiro Morisawa
St. Marianna University School of Medicine Department of Emergency and Critical Care Medicine
Outcome results
None listed