Safety and efficacy of accelerated corneal crosslinking for progressive keratoconus

Safety and efficacy of accelerated corneal crosslinking for progressive keratoconus - Accelerated corneal crosslinking for keratoconus

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000011492

Enrollment

Registered

2013-08-15

Start date

2013-02-21

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Keratoconus

Interventions

Accelerated corneal crosslinking

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with keratoconus 2. Keratoconus is progressing within recent 2 years. 2. The thinnest corneal thickness must be more than 400 micrometer

Exclusion criteria

Exclusion criteria: 1. Thinnest corneal thickness is less than 400 micrometer. 2. Those who are implanted cardiac pacemaker, or other medical devices. 3. Non-progressing keratoconus 4. Those who had other ophthalmic disorders. 5. Those who had general disorders that may impede corneal wound healing 6. In pregnancy, or presently breastfeeding 7. Occupation not allowed corneal refractive surgeries 8. Age less than 14 years-old

Design outcomes

Primary

Measure	Time frame
Visual acuity, manifest refraction, keratometric value, corneal endothelial cell number	—

Countries

Japan

Contacts

Public ContactKazuno Negishi

Keio University School of Medicine Department of Ophthalmology

fwic7788@mb.infoweb.ne.jp03-3353-0149

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026