Infusion of Donor Feces for Recurrent Clostridium difficile Infection

Infusion of Donor Feces for Recurrent Clostridium difficile Infection - Donor Feces for Clostridium difficile Infection

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000011481

Enrollment

Registered

2013-10-01

Start date

2014-01-27

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Reccurent Clostridium difficile infection

Interventions

Infusion of feces from healthy donor.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Recurrent C. difficile infection even with enough treatment, i.e. vancomycin or metronidazole for more than 10 days.

Exclusion criteria

Exclusion criteria: 1) Receiving other antibiotics for C. difficile infection. 2) Receiving prednisolone 1 mg/kg/day or more. 3) Treated in intensive care unit. 4) Receiving vasopressors. 5) Receiving immunosuppressants intravenously. 6) Receiving antibiotics for the purpose of digestive decontamination except for trimethoprim/sulfamethoxazole.

Design outcomes

Primary

Measure	Time frame
Relapse rate of C. difficile infection within 10 weeks after donor fece infusion.	—

Secondary

Measure	Time frame
Disappearance of diarrhea. Negative C. difficile toxin. Change in enteric flora.	—

Countries

Japan

Contacts

Public ContactNozomu Kawashima

Nagoya University Graduate School of Medicine Department of Pediatrics

kwnozomu@med.nagoya-u.ac.jp+81-52-744-2294

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026