Non-small cell lung cancer patients with COPD.
Conditions
Interventions
Tiotropium 18&
#13197
once daily for 13 weeks.
Tiotropium 18&
once daily with budesonide / formoterol combination drug 2 inhalation twice a day (morning and night time ) for 13 weeks.
Sponsors
Hamamatsu University School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Age is full 20 or older-year patients at the time of agreement acquisition. 2) The patient of a perioperative period whom the examination doctor in charge diagnosed as lung cancer based on lung cancer handling agreement (the 7th edition) 3) The patient whom COPD diagnosis and a treatment guideline machine companion examination doctor in charge diagnosed as COPD 4) The patient who used tiotropium more than four week for COPD treatment. 5)Patients who agreed to participate in the study and signed informed consent form.
Exclusion criteria
Exclusion criteria: 1)Patient that there is ICS/LABA mixing medicine in pre-administering within four weeks 2)Patient where exacerbation of COPD was admitted within four weeks 3)Patient that there is past of hypersensitivity in atropine, the kind edge material or tiotropium, budesonide or formoterol 4)Patient who has chronic ailments of lungs, heart, kidney, liver, and blood, etc. 5)Patient who has previous history of adrenal cortical insufficiency or accentuation syndrome 6)Patient who has glaucoma 7)Patient who has dysuria such as dysuria by enlarged prostate 8)Case who judged doctor in charge targets and it is improper
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Exacerbation rate of 12 weeks after the operation. (The extension of hospitalization, the infectious disease or the additional dosage of the antibiotic and administering a systemic steroid and the decrease in the respiratory function; The sum total of each event that falls below the predictive value by 10% or more at the time of 12 of the week of after the operation is divided in the population). | — |
Countries
Japan
Contacts
Public ContactKazuhito Funai
Hamamatsu University School of Medicine Surgery 1
Outcome results
None listed