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Investigation on efficacy of memantine in patients with Alzheimer's disease.

Investigation on efficacy of memantine in patients with Alzheimer's disease. - Efficacy of memantine in patients with Alzheimer's disease.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000011392
Enrollment
50
Registered
2013-08-12
Start date
2013-08-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alzheimer&#39

Interventions

12-month study evaluated the treatment effect and response of memantine in AD patients. 12-month study evaluated the treatment effect and response of memantine in AD patients.

Sponsors

Kawasaki Medical School
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients 1) who are Alzheimer's disease, 2) MMSE 0-20, 3) CDR 1-3, FAST stage 2-7, 3) TYM-J 0-34/50, 4) who understand the points of this study and give informed-consent in literature.

Exclusion criteria

Exclusion criteria: 1)Patients who correspond to the administration contraindication o the obhective drug. 2)Patients inadequate for the study.

Design outcomes

Primary

MeasureTime frame
Changes from baseline at week 48 on NPI

Secondary

MeasureTime frame
Changes from baseline at week 48 on MMSE, TYM-J, Zarit Burden Interview

Countries

Japan

Contacts

Public ContactYumiko Kutoku

Kawasaki Medical School neurology

kutoku@med.kawasaki-m.ac.jp086-462-1111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026