postherpetic neuralgia
Conditions
Interventions
oral ascorbate (1000 mg/day) given for 4 weeks
intravenous ascorbate (3,500 mg) administered eight times within 4 weeks
Sponsors
Chi Mei Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) diagnosis of postherpetic neuralgia (PHN) criteria - having PHN for at least 3 months but no longer than 2 years after ruling out other possible polyneuropathies and having an average daily spontaneous pain rated at least score 3 on an eleven point numeric rating pain scale (11- point NRS) from 0 to 10 (with 0 being no pain at all and 10 being the worst pain imaginable); (2) age ranged from 18 to 85; (3) female patients who were non-pregnant and non-lactating.
Exclusion criteria
Exclusion criteria: Patients were excluded if blood level of uric acid was higher than 7.0
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The changes in plasma ascorbate concentrations compared to the baseline-ascorbate concentrations after intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| The changes in daily average scales of spontaneous pain on the 11-point NRS measurement and the response rates after intervention | — |
Countries
Asia(except Japan)
Contacts
Public ContactMiao-Lin Hu
National Chung Hsing University, Taichung, Taiwan Department of Food Science and Applied Biotechnology
Outcome results
None listed