indications for oral anticoagulants ischemic heart disease
Conditions
Interventions
Perform single use of ADP receptor antagonists in patients taking oral anticoagulants undergoing coronary stenting.
Sponsors
Department of cardiovascular medicine, Kyoto University Graduate School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients sheduled for percutaneous coronary intervention. 2) Patients taking oral anticoagulants and patients start oral anticoagulant therapy after percutaneous coronary intervention.
Exclusion criteria
Exclusion criteria: 1) Contraindication of ADP receptor antagonists. 2) Pregnant women, women suspected of being pregnant, and breast-feeding women. 3) Judged as ineligible for enrollment by clinical investigators. 4) Past medical history of stent thrombosis. 5) Patients who cannot change current antiplatelet agents, including aspirin, cilostazol, and ticlopidine.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Composite endpoint of all-cause death, myocardial infarction, stent thrombosis, and stroke. Major bleeding (BARC Type 3 or 5). | — |
Secondary
| Measure | Time frame |
|---|---|
| All-cause death, myocardial infarction, stroke, stent thrombosis, coronary revascularization, admission by angina pectoris, and admission by heart failure. | — |
Countries
Japan
Contacts
Public ContactToshiaki Toyota
Kyoto University Graduate School of Medicine Cardiovascular Medicine
Outcome results
None listed