Comparison of curative effect of latanoprost and unoprostone in patients with nomal tension glaucoma (IOP<=15mmHg).

Comparison of curative effect of latanoprost and unoprostone in patients with nomal tension glaucoma (IOP<=15mmHg). - Comparison of curative effect of latanoprost and unoprostone in patients with nomal tension glaucoma (IOP<=15mmHg).

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000011320

Enrollment

100

Registered

2013-07-30

Start date

2007-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma

Interventions

Using latanoprost for 3 years. Using unoprostone for 3 years.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with normal tension glaucoma setting following conditions. 1)IOP <= 15 mmHg in no medication. 2)MD >= -12 dB and difference of right and left MD <= 6 dB. 3)Not applicable to contraindication or careful administration of these drugs. 4)Corrected visual acuity >= 0.8 5)Spherical refraction is within &#8211;9D to +9D. 6)Difference of right and left Spherical refraction <=3D 7)No any intraocular eye disease 8)No history of intraocular surgery or laser treatment. 9)Subjects who agree to the participation in this study.

Exclusion criteria

Exclusion criteria: Patients not satisfying the above conditions

Design outcomes

Primary

Measure	Time frame
To study MD of baseline and 3 years later using latanoprost and unoprostone.	—

Secondary

Measure	Time frame
1) To study CPSD or TD of baseline and 3 years later using latanoprost and unoprostone. 2) To study transition MD, CPSD or TD of baseline to 3 years later using latanoprost and unoprostone. 3) To comparare MD, CPSD or TD between groups of using latanoprost and unoprostone for 3 years. 4) To study transition IOP of baseline to 3 years later using latanoprost and unoprostone. 5) To comparare IOP between groups of using latanoprost and unoprostone. 6) Adverse events in each groups.	—

Measure

Time frame

1) To study CPSD or TD of baseline and 3 years later using latanoprost and unoprostone. 2) To study transition MD, CPSD or TD of baseline to 3 years later using latanoprost and unoprostone. 3) To comparare MD, CPSD or TD between groups of using latanoprost and unoprostone for 3 years. 4) To study transition IOP of baseline to 3 years later using latanoprost and unoprostone. 5) To comparare IOP between groups of using latanoprost and unoprostone. 6) Adverse events in each groups.

—

Countries

Japan

Contacts

Public ContactKazuhisa Sugiyama

Kanazawa University Department of Ophthalmology

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026

Comparison of curative effect of latanoprost and unoprostone in patients with nomal tension glaucoma (IOP&lt;=15mmHg).