Examination of ocular blood flow and reduction of intraocular pressure, comparing Tafuluprost and Tafuruprost Bunazosin with primary open angle Glaucoma.

Examination of ocular blood flow and reduction of intraocular pressure, comparing Tafuluprost and Tafuruprost Bunazosin with primary open angle Glaucoma. - Examination of ocular blood flow and reduction of intraocular pressure, comparing Tafuluprost and Tafuruprost Bunazosin with primary open angle Glaucoma.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000011319

Enrollment

Registered

2013-07-30

Start date

2009-02-19

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma

Interventions

Eye drops of tapuros (once daily) for one month. Then add detantole (twice daily) for next one month.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Both eyes was diagnosed glaucoma and untreatmented more than one month. 2) Subject eye is primary open angle glaucoma atleast.And fellow eye can undergo the treatment during test period 3) Outpatients or inpatients. 4) Patients who agreed and signed to the participation in this study. 5) Patients who can observed the schedule written in trial implementation protocol. 6) IOP(fellow eye)<=30

Exclusion criteria

Exclusion criteria: 1) Patients who have ocular diseases without glaucoma and mild cataract(diabates retinopathy or morbid myopia or etc) 2) Progressive or severe glaucoma(for example using a Humphery field analyzer,MD <-12dB,0dB detection is in 5degree) 3) Patients with any corneal abnormality or other condition preventing reliable applanation tonometry. 4) Patients with anamnestic hitory of hypersensitivity to prostagrandin analogs and benzalkonium chloride. 5) Patients with active external ocular diseases,ocular inflammation or infection. 6) Patients with history of reflactive surgery. 7) Patients with history of internal ocular surgery within 6month before the study (cataract surgery,SLT,trabecrctomy,trabecrotomy etc). 8) Smoker 9) Patients who are unable to undergo ocular blood flow test. 10) Pregnant,lactating women ,the women who desired of the pregnancy during the test period. 11) Patients who are going to use prohibited drugs during test period. 12) Doctor judged to be inelible to the study.

Design outcomes

Primary

Measure	Time frame
Ocular blood flow	—

Secondary

Measure	Time frame
Intraocular pressure	—

Countries

Japan

Contacts

Public ContactKazuhisa Sugiyama

Kanazawa University Department of Ophthalmology

ksugi@med.kanazawa-u.ac.jp076-265-2403

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026