Comparison of intraoperative relatively high-dose and low-dose remifentanil for postoperative epidural analgesia after gynecological abdomonal surgery

Comparison of intraoperative relatively high-dose and low-dose remifentanil for postoperative epidural analgesia after gynecological abdomonal surgery - Intraoperative remifentanil for postoperative epidural analgesia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000011185

Enrollment

Registered

2013-07-13

Start date

2009-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gynecological abdominal surgery

Interventions

In the high-dose remifentanil group, while an end-tidal sevoflurane concentration was maintained at 1.2% throughout anaesthesia, a remifentanil infusion was started at a rate of 0.25 ug/kg/min and sub

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: patients undergo elective gynaecological abdominal surgery with lower abdominal incision below umbilicus

Exclusion criteria

Exclusion criteria: Patients were not excluded if they had diabetes, chronic pain, psychiatric illness, a preoperative use of opioid analgesics, a history of drugs or alcohol abuse, or were unable to use a patient-controlled analgesia (PCA) device. Patients were also excluded if there were any contraindications to epidural catheter placement, or if they refused epidural catheter placement.

Design outcomes

Secondary

Measure	Time frame
pain intensity assessed with the Prince Henry pain scale	—

Primary

Measure	Time frame
cumulative amount of local anesthetics at 48 h after surgery	—

Countries

Japan

Contacts

Public ContactYamashita, Soichiro

University of tsukuba Faculty of Medicine

soichiyamashita@md.tsukuba.ac.jp

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026