Prophylaxis of febrile neutropenia by reducing chemotherapy-induced gastrointestinal mucosal injury

Prophylaxis of febrile neutropenia by reducing chemotherapy-induced gastrointestinal mucosal injury - Prophylaxis of febrile neutropenia

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000011065

Enrollment

Registered

2013-07-01

Start date

2014-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

febrile neutropenia

Interventions

oral administration of synbiotics oral administration of glutamine oral administration of synbiotics and glutamine control

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients admitted for cancer chemotherapy which is expected to cause neutropenia

Exclusion criteria

Exclusion criteria: patients with underlying infection before developping neutropenia patients who is allergic to probiotics or glutamine

Design outcomes

Primary

Measure	Time frame
incidence of febrile neutropenia	—

Secondary

Measure	Time frame
severity of gastrointestinal mucosal injury stability of intestinal environments	—

Countries

Japan

Contacts

Public ContactTomoko Kurimoto

Juntendo University School of Medicine Department of Pediatrics and Adolescent Medicine

tkurashi@juntendo.ac.jp03-3813-3111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026