gastrointestinal neoplasms to be resected by endoscopic submucosal dissection (ESD)
Conditions
Interventions
Covering mucosal defects made after ESD with Neoveil and Beriplast
Sponsors
the Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Adult patients who will undergo ESD at our hospital and have given written informed consent to this study. And those who have a risk of developing complications: (1) ESD for large neoplasm is scheduled; (2) heparinization during cessation of antithrombotic drugs is applied; and so on.
Exclusion criteria
Exclusion criteria: 1. Those who fall under the category of contraindication of Neoveil or Beriplast. Neoveil: those who have systematic complications Beriplast: 1) those who have a history of anaphylaxis to components of Beriplast or drugs made of bovine lung, such as aprotinin 2) those who are treated with procoagulants (hemocoagulase made from snake venom), antifibrolytic agents, and aprotinin 2. Those who are considered to be inappropriate for this study by doctors
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The rate of complications after ESD in conjunction with the covering method with Neoveil and Beriplast. | — |
Secondary
| Measure | Time frame |
|---|---|
| procedure time / success rate of covering / complications associated with the procedure / body temperature, the number of white blood cell, the value of C-reactive protein, and the presence of abdominal pain the next day after ESD | — |
Countries
Japan
Contacts
Public ContactYosuke Tsuji
Graduate School of Medicine, University of Tokyo Department of Gastroenterology
Outcome results
None listed