Effect of continuous infusion of phenylephrine on maternal cerebral blood flow and oxygenation during spinal anesthesia for cesarean section; prospective randomized control trial

Effect of continuous infusion of phenylephrine on maternal cerebral blood flow and oxygenation during spinal anesthesia for cesarean section; prospective randomized control trial - Effect of continuous infusion of phenylephrine on maternal cerebral blood flow and oxygenation during spinal anesthesia for cesarean section

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000010993

Enrollment

Registered

2013-06-24

Start date

2013-06-24

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Full term pregnancy

Interventions

Continuous infusion of saline, at a rate of 1 ml/min, during 20 min after intrathecal injection of bupivacaine Continuous infusion of phenylephrine, at a rate of 25 mcg/min, during 20 min after intrat

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Healthy full-term pregnant woman aged over 18, undergoing elective cesarean section under spinal anesthesia

Exclusion criteria

Exclusion criteria: Patient with a diagnosis of hypertension, diabetes and renal dysfunction due to pregnancy, and obese patient whose BMI >30

Design outcomes

Primary

Measure	Time frame
Change in maternal cerebral blood flow and oxygenation during spinal anesthesia for cesarean section evaluated by near infrared spectroscopy (NIRS)	—

Countries

Japan

Contacts

Public ContactNoriya Hirose

Nihon University School of Medicine Division of Anesthesiology, Department of Anesthesiology

hirose.noriya@nihon-u.ac.jp03-3972-8111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026