Study of the improvement effect of proton pump inhibitors for gastric ulcers after endoscopic submucosal dissection (ESD): a randomized comparative study of omeprazole iv vs. esomeprazole po

Study of the improvement effect of proton pump inhibitors for gastric ulcers after endoscopic submucosal dissection (ESD): a randomized comparative study of omeprazole iv vs. esomeprazole po - Study of the improvement effect of proton pump inhibitors for gastric ulcers after endoscopic submucosal dissection (ESD): a randomized comparative study of omeprazole iv vs. esomeprazole po

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000010958

Enrollment

200

Registered

2013-06-13

Start date

2012-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastric cancer

Interventions

In the esomeprazole group, taking one tablets of esomeprazole from one day before ESD In the omeprazole group, intravenous drip infusion of omeprazole for 2days after ESD,and taking 1 tablets of ome

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Patients with gastric cancer treated by ESD 2.No previous chemotherapy or radiotherapy or operation for gastric cancer 3.ECOG Performance status(PS): 0, 1, 2 4.Sufficient organ functions 5.Written infromed consent

Exclusion criteria

Exclusion criteria: 1.Active gastric or duodenal ulcers 2.Taking continuous systemic steroids 3.Taking NSAIDs 4.Psychiatric disease that is inappropriate for entry into this study 5.Patients whom the doctor decide as not proper for the study

Design outcomes

Primary

Measure	Time frame
Retio of delayed bleeding	—

Countries

Japan

Contacts

Public ContactShinya Yamada

Ishikawa Prefectural Central Hospital Department of Gastroenterology

s.yamada@ipch.jp076-237-8211

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026