Multi-Institutional Collaborative Cohort Study on the improvement of marker for diabetes mellitus and oral malodor by periodontal treatment (MICCS-DOP)

Multi-Institutional Collaborative Cohort Study on the improvement of marker for diabetes mellitus and oral malodor by periodontal treatment (MICCS-DOP) - Improvement of DM and halitosis by periodontal treatment

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000010938

Enrollment

300

Registered

2013-07-01

Start date

2013-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes Mellitus Periodontal Disease

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: A) Moderate diabetic outpatient under treatment for diabetes (fasting blood sugar: over 126 mg/dl or HbA1c[NGSP]: over 6.5% ) B) New patient with periodontal disease: Patients with suspected diabetes (in the case of the refference from dental clinc to medical clinic) C) Healthy subject without diabetes and periodontal disease

Exclusion criteria

Exclusion criteria: A) Patient with a serious liver disease or renal disease B) Patient with malignant tumor C) Poorly controlled diabetic patient (fasting blood sugar: over 160 mg/dl or HbA1c[NGSP]: over 8.4% ) D) Patient scheduled for surgery E) In addition, patient being deemed inappropriate as subject in this study by the dentist

Design outcomes

Primary

Measure	Time frame
1. test value for diabetes mellitus: HbA1c, LDL, HDL, TG, FBS 2. test value for periodontal desease: pocket depth, bleeding on probing, tooth mobility, IgG titer against periodontal pathogens, bone loss index 3. halitosis test level: bless checker level 4. Inflammatory marker: WBC, hs-CRP	—

Countries

Japan

Contacts

Public ContactShogo Takashiba

Okayama University Department of Pathophysiology - Periodontal Science, Graduate School of Medicine, Dentistry and Pha

stakashi@cc.okayama-u.ac.jp086-235-6675

Outcome results