febrile neutropenia
Conditions
Interventions
Administration of antibiotics (sitafloxacin)
Sponsors
Lung Oncology Group in Kyushu, Japan (LOGIK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Informed consent is obtained 2.Patient who is judged as an appropriate case by the doctor in charge 3.At least 20 years of age 4. Patient who had lung cancer accompanied by chemotherapy-induced neutropenia with a polymorphonuclear neutrophil count of less than 1000/mm3 and a temperature of 37.5 C MASCC score of 21 or above
Exclusion criteria
Exclusion criteria: 1. Patient who is too severely ill 2. A history of renal failure (S-Cr of 2.0 mg/dl or above) 3. A known history of hypersensitivity to fluoroquinolones 4. A known history of allergy 5. Patient who is not evaluated for response 6. Pregnant or lactating women. 7. Patients administered with prohibiting medication (such as other antibiotics, gamma-globulin, corticosteroid) 8.patient who is judged as an inappropriate case by the doctor in charge
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Response rate | — |
Secondary
| Measure | Time frame |
|---|---|
| Defervescence at 72 hours, 7 days, 14 days Safety | — |
Countries
Japan
Contacts
Public ContactMasaki Fujita
Fukuoka University, Faculty of Medicine Department of Respiratory Medicine
Outcome results
None listed