Hepatocellular carcinoma (HCC)
Conditions
Interventions
EOB-enhanced MRI/enhanced MDCT
Sponsors
Osaka Liver Study Group for Diagnosis,Treatment and Prevention of Hepatocellular Carcinoma
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Hypervascular HCC diagnosed on the basis of one of the following criteria and treated by radiofequency ablation within one month after diagnosis of HCC. *Definition of hypervascular HCC a)Early stain on arterial phase and washout on late phase of dynamic CT or Gd-EOB-DTPA-enhanced MRI. b)Early stain on arterial phase, washout on late phase and hyperintensity on hepatobiliary phase of Gd-EOB-DTPA-enhanced MRI. When hypovascular tumor more than 1.5cm in diameter is present, it should be diagnosed by liver biopsy and be treated in case of HCC. 2. =>20 years old at the time of entry 3.Body weight <100kg 4.Any cause of underlying liver disease
Exclusion criteria
Exclusion criteria: 1.Extrahepatic liver metastasis 2.History of any cancer other than HCC within 5 years 3.Contraindication for MRI 4.Hypersensitivity to contrast agents of MRI or CT 5.Cirrhosis of Child-Pugh grade C 6.Hepatic encephalopathy of more than grade 2 7.Serum total bilirubin level of => 3 mg/dl 8.Patients judged as unsuitable for this study by the investiagators
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Detection sensitivity of recurrence of hypervascular hepatocellular carcinoma after RFA between dynamic CT and GD-EOB-DTPA-enhanced MRI | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of tumors of recurrence of hepatocellular carcinoma after RFA between dynamic CT and GD-EOB-DTPA-enhanced MRI | — |
Countries
Japan
Contacts
Public ContactYasuharu Imai
Ikeda Municipal Hospital Department of Gastroenterology
Outcome results
None listed