early esophageal cancer
Conditions
Interventions
We do the steroid pulse therapy to prevent strictures after endoscopic submucosal dissection (ESD) for esophageal cancer
Sponsors
Fukushima Medical University School of Medicine, Department of Gastroenterology
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patient who will be performed endoscopic treatment for esophageal cancer. 2. Absolute or relative indication of endoscopic treatment within the therapy guidelines for esophageal cancer. 3. ESD is planned for esophageal cancer, and expected to result of a size of not less than three quarters of the circumference. 4. Patient with no prior chemotherapy, radiotherapy, and surgical treatment. 5. ECOG-Perfomance Status is 0 or 1. 6. Adult Patients aged upper 20 years old. 7. Patient with adequate liver and renal function. 8. Patient must sign an informed consent.
Exclusion criteria
Exclusion criteria: 1. Patient with active peptic ulcer in stomach and duodenum. 2. Patient has a history of tuberculosis. 3. Patients who had an acute myocardial infarction. 4. Patients with uncontrolled diabetes mellitus. 5. Patients with continuous systemic steroids medication. 6. Patients with continuous systemic NSAIDs. 7. Patients temporary interruption of antiplatelet agents and anticoagulants is not possible. 8. Patients with severe mental disease or psychotic manifestation. 9. Patients who have been judged as inappropriate for this study for any reasons by the concerning investigation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Strictures after ESD | — |
Secondary
| Measure | Time frame |
|---|---|
| Safety of steroid pulse therapy | — |
Countries
Japan
Contacts
Public ContactHikichi Takuto
Fukushima Medical University Hospital Department of Endoscopy
Outcome results
None listed