Clinical evaluation on activation of coagulation and fibrinolytic system during major cardiovascular surgery

Clinical evaluation on activation of coagulation and fibrinolytic system during major cardiovascular surgery - Clinical evaluation on activation of coagulation and fibrinolytic system during major cardiovascular surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000010866

Enrollment

Registered

2013-06-17

Start date

2013-04-14

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

major cardiovascular surgery with use of cardiopulmonary bypass

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: aortic replacement surgery,other cardiovascular surgery,re-surgery for cardiovascular replacement

Exclusion criteria

Exclusion criteria: patients with congenital bleeding diathesis, patients with thrombocytopenia less than 100,000/uL continuing more than one month, patients with taking oral anticoagulant/antiplatelet agents

Design outcomes

Primary

Measure	Time frame
activated factor VII, thrombin-antithrombin complex (TAT), fibrin monomer, fibrin degradation product (FDP), D-dimer, plasmin-plasmin inhibitor complex (PIC), fibrinogen, PT, APTT, platelet count, hemoglobin, from just before the start of cardiopulmonary bypass until entrance into the intensive care unit	—

Countries

Japan

Contacts

Public ContactSATO HIDEO

Teikyo University Hospital anesthesiology

hideos3150@yahoo.co.jp03-3964-1211

Outcome results