Benign or malignant pulmonary lesions
Conditions
Interventions
Virtual images toward pulmonary peripheral lesions are produced using Directpath. Transbronchial biopsy (TBB) with virtual bronchoscopic navigation (VBN) is performed using a 2.8-mm ultrathin bronch
channel inner diameter, 1.2 mm
Olympus). Subsequently, endobronchial ultrasound-guided transbronchial biopsy (EBUS-TBB) /transbronchial needle aspiration (TBNA) with VBN is performed using a 4.0-mm bronchoscope (BF-P260F, inner dia
Olympus).
Sponsors
Gifu Prefectural General Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. On chest CT images, an abnormal shadow is present in the peripheral area of the lung field, and bronchoscopy is necessary to make a diagnosis or determine treatment principles 2. 20 years of age or older 3. Consent in writing to participate in this study has been obtained from patients themselves
Exclusion criteria
Exclusion criteria: 1. Case with serious concomitant medical illness 2. Central pulmonary lesions 3. Diffuse pulmonary lesions 4. Re-examination due to prior failure in this trial 5. Case with pure ground glass opacity 6. Patients needing to undergo other bronchoscopic procedures (e.g. TBNA, BAL) 7. Bleeding tendency 8. Pregnant woman 9. Other clinical difficulties in this trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnostic yield | — |
Secondary
| Measure | Time frame |
|---|---|
| Directpath The bronchial generation order allowing automatic virtual image production The bronchial generation order for which manual registration is added Bronchoscope Consistency with virtual images The bronchial generation order allowing insertion and the outer diameter of the bronchus on virtual images The distance from the bronchoscope insertion site to the lesion and the number of bronchial divisions The bronchial generation order allowing observation The bronchial generation order allowing observation Diagnostic yield Diagnostic yields according to the method and bronchoscope used Diagnostic yield according to the lesion size Diagnostic yields according to the distance between the lesion and hilum Diagnosis yields according to the lesion visualization rate using ultrasound, whether the lesion is visualized, and the positional relationship between the ultrasound probe and lesion Visibility on EBUS. Diagnostic yield according to location of probe in relation to target lesion Examination time Safety, Complications | — |
Countries
Japan
Contacts
Public ContactAkifumi Tsuzuku
Gifu Prefectural General Medical Center Department of Pulmonary Medicine and Bronchoscopy
Outcome results
None listed