Skip to content

Emergence agitation in pediatric patients after sevoflurane anesthesia without nitrous oxide or combination with nitrous oxide

Emergence agitation in pediatric patients after sevoflurane anesthesia without nitrous oxide or combination with nitrous oxide - emergence agitation after sevoflurane without nitrous oxude

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000010763
Enrollment
42
Registered
2013-05-20
Start date
2013-05-20
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

tonsillectomy and adenoidectomy surgery

Interventions

anesthesia was maintained with sevoflurane alone in the group S anesthesia was maintained with 50% N2O and sevoflurane in the group N

Sponsors

Korea University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: patients scheduled for elective surgery of tonsillectomy and adenoidectomy

Exclusion criteria

Exclusion criteria: Patients with a history of cardiovascular, respiratory (asthma), neurologic (seizure), kidney, liver disease, mood disorder, prematurity, or developmental delay, the presence of upper respiratory infection, hypersensitivity to drugs, and those receiving analgesics, sedatives or psychiatric medication were excluded.

Design outcomes

Primary

MeasureTime frame
Anesthetic maintenance using sevoflurane without nitrous oxide is associated with a higher end tidal concentration of sevoflurane at emergence than sevoflurane with nitrous oxide; however, this difference may be dose-related. The anesthetic properties of these two maintenance methods do not seem to have a role in the incidence of emergence delirium or recovery profile.

Countries

Asia(except Japan)

Contacts

Public ContactIl-Ok Lee

Korea University Anesthesiology and Pain Medicine

iloklee@korea.ac.kr82-2-2626-3234

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026