Randomized contol trials of immunonutrition in perioperative management for hepato-pancreatico-biliary surgery

Randomized contol trials of immunonutrition in perioperative management for hepato-pancreatico-biliary surgery - IM-RCT

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000010760

Enrollment

120

Registered

2014-10-01

Start date

2012-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hepato-pancreatico-biliary malignancy

Interventions

Perioperative conventional nutritional therapy Peioperative immunonutrition

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. The patients who underwent hepato-pancreatico-biliary elective surgery with digestive tract dissection 2. Patient age is 20-80 years old 3. American Society of Anesthesiologists score 1-3 4. Provision of written informed consent

Exclusion criteria

Exclusion criteria: 1. Bodyweight (BW) loss of 10 per cent or more within 6months before entry. 2. Performance status 2 or more on the Eastern Cooperative Oncology Group scale 3. Hepatic dysfunction (Child-Pugh score B or more) 4. Renal function (serum creatinine level > 1.8mg/dl) 5. Insulin-dependent diabetes mellitus 6. Concurrent active infection 7. The patients who determined to be inappropriate clinically as a sublect for this study

Design outcomes

Primary

Measure	Time frame
Occurrence of infectious complication	—

Countries

Japan

Contacts

Public ContactHiroaki Motoyama

Shinshu University First department of surgery

motoyama@shinshu-u.ac.jp

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026