Investigation for the effects of hydrogen rich water on chronic hepatitis and liver cirrhosis

Investigation for the effects of hydrogen rich water on chronic hepatitis and liver cirrhosis - Hydrogen rich water for chronic hepatitis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000010693

Enrollment

Registered

2013-05-20

Start date

2013-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic hepatitis and liver cirrhosis

Interventions

GroupA:drink hydrogen rich water 1L/day for 1month, following 1month washout and drink control water 1L/day for 1month. GroupB:drink control water 1L/day for 1month, following 1 month washout and dri

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)chronic hepatitis or liver cirrhosis diagnosed with liver biopsy or radiography and show ALT elevation with standard therapy. 2)Patients whose ALT levels kept beyond upper limit of normal range for more than 2 months.

Exclusion criteria

Exclusion criteria: 1)Patients who need albumin administration more than once /week for 1 month or more. 2)Patients with edema or ascite. 3)Patients with hepatic encephalopathy. 4)Bilirubin levels equal or >2mg/dl. 5)Albumin levels <3g/dl. 6)Serum Na <130 mEq/L 7)Alcohol abuser. 8)Creatinin equal or >1.3mg/dl. 9)Patients who are receiving interferon treatment. 10)Family Doctors comment

Design outcomes

Primary

Measure	Time frame
Reduction of high ALT	—

Countries

Japan

Contacts

Public ContactAkinobu Takaki

Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences. Department of Gastroenterology and Hepatology

akitaka@md.okayama-u.ac.jp086-235-7219

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026