Patients undergoing cardiac surgery
Conditions
Interventions
None listed
Sponsors
Department of Anesthesiology, Tokyo Medical and Dental University, Graduate School of Medicine
The University of Tokyo Hospital Yokohama City University Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients undergoing elective cardiac surgery listed below (1) Aortic surgery (2) Valve surgery (3) Offpump coronary artery bypass grafting
Exclusion criteria
Exclusion criteria: Preoperative exclusion criteria were: 1) patient's age < 20 years; 2) history of myocardial infarction within 30 days before the day of surgery; 3) preoperative diagnosis of pneumothorax; 4) diagnosis of chronic obstructive pulmonary disease; 5) neuromuscular disease; 6) morbidly obese (body mass index > 40); and 7) systemic connective tissue disease. Postoperative exclusion criteria were: 1) severe neurological complications requiring mechanical ventilation; 2) the need for an extracorporeal circuit due to cardiac failure; and 3) patients whose pulmonary artery occlusion pressure (PAOP) was >18 mm Hg in the first postoperative week.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Relationship between RAGE levels and duration of mechanical ventilation | — |
Secondary
| Measure | Time frame |
|---|---|
| Relationships between RAGE and other biomarker proteins (interleukin-8, S100/A12, Angiopoietins, von Willbrand factor antigen, HMGB1 etc) | — |
Countries
Japan
Contacts
Public ContactTokujiro Uchida
Tokyo Medical and Dental University Graduate School of Medicine Department of Anesthesiology
Outcome results
None listed