phase III Randomized study between retroperitoneal lymphadenectomy with and without caudal external iliac lymph nodes on lymphedema of the lower extremities after surgeries of endometrial cancer (a randomized study by multi-institutes)

phase III Randomized study between retroperitoneal lymphadenectomy with and without caudal external iliac lymph nodes on lymphedema of the lower extremities after surgeries of endometrial cancer (a randomized study by multi-institutes) - P III study on lymphedema of the lower extremities of endometrial cancer

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000010650

Enrollment

150

Registered

2013-06-01

Start date

2013-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometrial cancer

Interventions

peritoneal lymphadenectomy with caudal external iliac lymph nodes peritoneal lymphadenectomy without caudal external iliac lymph nodes

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1) Patients who were diagnosed endometrial cancer by histopathological examination. 2) Patients who will be performed retroperitoneal lymph node dissection. 3) Performance status 0 or 1 1) Patients who were Informed and concented.

Exclusion criteria

Exclusion criteria: 1) Patients with a primary lymphedema or a past histry of lymphedema due to infection 2) Patients who are estimated lymph node metastasis or/and distant metastasis by CT or PET-CT. 3) Patients who were underwent past radiotherapy or chemotherapy. 4) Patients who are regarded as inadequate ones due to other reasons (e.g. severe varix of the lower extremities)

Design outcomes

Primary

Measure	Time frame
To compare the cumulative incidences of lymphedema after retroperitoneal lymphadenectomy between with and without caudal external iliac lymph nodes among three years after the surgeries.	—

Secondary

Measure	Time frame
To compare the cumulative incidences of lymphedema after retroperitoneal lymphadenectomy between with and without caudal external iliac lymph nodes among three years after the surgeries.	—

Countries

Japan

Contacts

Public ContactHiroshi Sasaki

The Tokyo Jikei University School of Medicine Kashiwa Hospital, Dept. of OB. & GYN.

hrssasaki@jikei.ac.jp04-7164-1111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026