The Effects of Epidural Anesthesia on Postoperative Nausea and Vomiting in Patients Undergoing Laparoscopic Gynecologic Surgery

The Effects of Epidural Anesthesia on Postoperative Nausea and Vomiting in Patients Undergoing Laparoscopic Gynecologic Surgery - The Effects of Epidural Anesthesia on Postoperative Nausea and Vomiting in Patients Undergoing Laparoscopic Gynecologic Surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000010617

Enrollment

Registered

2013-05-06

Start date

2013-05-07

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients undergoing laparoscopic gynecologic surgery.

Interventions

General anesthesia General anesthesia combined with epidural anesthesia

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Patients who meet two or more criteria in Apfel's simplified score. (Female gender, non-smoker, motion sickness or history of PONV and postoperative opioid use).

Exclusion criteria

Exclusion criteria: Emergency surgery Contraindication to the use of any of the study medications Contraindication to epidural anesthesia Patients who took antiemetics and/or analgesics within 24h prior to the surgery

Design outcomes

Primary

Measure	Time frame
The incidence of PONV during 24h after the surgery.	—

Secondary

Measure	Time frame
The incidence of nausea, the number of vomiting and the use of rescue antiemetics administered at the post-anesthetic care unit and three postoperative intervals (T2: 0-2h, T12: 2-12h and T24: 12-24h) and total amount of rescue analgesics administered for 24h post-operation.	—

Countries

Japan

Contacts

Public ContactItsuo Nakatsuka

Saiseikai Central Hospital Department of Anesthesiology

PFA03271@nifty.com03-3451-8211

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026