A prospective cohort study to explore predictive factors to TS-1 plus platinum-based drugs in patients with squamous cell lung cancer YCRG10

A prospective cohort study to explore predictive factors to TS-1 plus platinum-based drugs in patients with squamous cell lung cancer YCRG10 - A prospective cohort study to explore predictive factors to TS-1 plus platinum-based drugs in patients with squamous cell lung cancer YCRG10

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000010564

Enrollment

Registered

2013-04-23

Start date

2013-04-24

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

squamous cell lung cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)Advanced squamous cell lung cancer patients(no prior chemotherapy) who is planned to receive TS-1 plus platinum-based drugs 2)Patients age is older than 20 when registration 3)Patients whoes blood samples( serum and whole blood) are available before treatment 4)Target lesion is evaluable 5)Written infomed consent from the patients

Exclusion criteria

Exclusion criteria: Patients whose participation in this study is judged to be inappropriate by the physicians

Design outcomes

Primary

Measure	Time frame
To evaluate correlation between tumor response and gene expression and protein levels in serum,whole blood and tissue	—

Secondary

Measure	Time frame
To evaluate correlation between PFS, OS, adverse events, relative dose intensity and gene expression and protein levels in serum,whole blood and tissue	—

Countries

Japan

Contacts

Public ContactMasaharu Shinkai

Yokohama City University Medical Center Respiratory Disease Center

shinkai@yokohama-cu.ac.jp045-261-5656

Outcome results