The deep hypnotic state of bispectral index values lower than 40 definitely attenuates rocuronium-induced withdrawal movement in children

The deep hypnotic state of bispectral index values lower than 40 definitely attenuates rocuronium-induced withdrawal movement in children - The deep hypnotic state reduces withdrawal caused by rocuronium in children

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000010545

Enrollment

156

Registered

2013-04-19

Start date

2013-04-19

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

minor elective surgery

Interventions

Rocuronium is administered at the loss of eyelash reflex Rocuronium is administered at the time of BIS under 40 Rocuronium is administered at the time of BIS under 40 after manual ventilation is prov

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Pediatric patients aged 3~12 years with a physical status of 1 (the American Society of Anesthesiologists rating) who are scheduled to undergo minor elective surgery

Exclusion criteria

Exclusion criteria: Patients with a history of cardiovascular, respiratory (asthma), neurologic (seizure), kidney, liver disease, mood disorder, prematurity, or developmental delay, the presence of upper respiratory infection, hypersensitivity to drugs, and those receiving analgesics, sedatives or psychiatric medication will be excluded. Patients with a vein that does not drain well or with redness, swelling and tenderness along the vein, and patients who had a history of difficult peripheral venous cannulation will be also excluded.

Design outcomes

Primary

Measure	Time frame
The incidence and grade of rocuronium-induced withdrawal movement	—

Countries

Asia(except Japan)

Contacts

Public ContactByung Gun Lim

Guro Hospital, Korea University College of Medicine Department of Anesthesiology and Pain Medicine

bglim9205@korea.ac.kr82-2-2626-1437

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026