Investigation of the usefulness of drug change from one type to another type of 5-ASA (5-mesalamine) in the treatment of ulcerative colitis during the relapse state

Investigation of the usefulness of drug change from one type to another type of 5-ASA (5-mesalamine) in the treatment of ulcerative colitis during the relapse state - Investigation of the usefulness of drug change from one type to another type of 5-ASA (5-mesalamine) in the treatment of ulcerative colitis during the relapse state

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000010544

Enrollment

Registered

2013-04-19

Start date

2013-04-05

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ulcerative colitis

Interventions

For patients who relapsed during the maintenance with Pentasa are changed to Asacol 3600mg/day for eight weeks. Patients, who relapsed during the maintenance with Asacol, are changed to Pentasa 400

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Ulceratice colitis patinets who relapsed during maintenance with Asacol or Pentasa Patients, 16 years or older, who gave written consent on attending this study after enough explanation. (For juveniles less than twenty years old, written consent of their parents is also needed.)

Exclusion criteria

Exclusion criteria: Patients with severe diarrhea (>10 times a day) whom their primary doctors judged them as difficult to treat with oral drug.&nbsp;

Design outcomes

Primary

Measure	Time frame
Reduction in CAI (Clinical Activity Index) four and eight weeks after the drug change	—

Secondary

Measure	Time frame
Reduction in EI (Endoscopic Index) four and eight weeks after the drug change	—

Countries

Japan

Contacts

Public ContactHiroshi Araki

Gifu university hospital Division of endoscopy

araara@gifu-u.ac.jp

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026